Multi-Centre Projects

The Network streamlines the process of setting up multi-centre studies by linking Centres, Working Groups, external advisors and funders, and by ensuring high capacity and harmonised data among all the sites.

Analysis of INDEPTH multi-centre studies shows that the Network’s Secretariat considerably reduced the cost of developing proposals and executing studies. Leveraging the Network to launch a study ensures:

Faster set-up: Multi-centre proposals arise from strategies and plans already developed by Working Groups co-ordinating with the Resource & Training Centre, they are faster to conceive teams that work together regularly. With a Working Group strategy in place, development of a successful proposal takes roughly half the time and half the cost of one developed from scratch.

Faster analysis: the standardised tools and database platforms implemented by the Network make it easier to merge and analyse data. They eliminate the costly process of data cleaning and harmonisation, enabling researchers to begin analysis almost immediately following data collection and entry.

Improved transparency: The INDEPTH Secretariat’s accounting team is always prepared to support multi-centre studies, reducing administrative costs and ensuring appropriate use of project funds. The Secretariat’s accounting processes have been audited by the Network’s institutional auditors (PWC, KPMG) and vetted by funders over the years, increasing their confidence in INDEPTH.

Project status

  • This study will assess and compare community-based antibiotic access and consumption and the factors that underpin them, in six countries in Africa and Asia.

  • To track progress towards the Every Newborn Action Plan (ENAP) vision to end preventable maternal and newborn deaths and stillbirths, data are on both outcomes and coverage of interventions are essential to ensure we are reaching those in need, especially

  • Enhancing Quality Malaria Care (EQMC)

  • EVIDENCE The study will generate and synthesize evidence to strengthen and contribute to the scale-up of high-quality family planning and reproductive health services in USAID priority countries.

  • The study aims to identify ways in which behavioral and biologic risks are embedded in the social and policy context and are driven by social and economic conditions.

  • The project works on improving estimation of Out-Of-Pocket expenditure (OOP) in a household survey and develop a set of questions to facilitate OOP specific disease measurement.

  • The study- INDEPTH Effectiveness and Safety Studies of Antimalarial Drugs in Africa (INESS) -aims to enable African researchers to carry out large Phase IV trials.

  • iSHARE2 enables INDEPTH member centres to contribute high-quality datasets and for INDEPTH to share longitudinal health and population data with the scientific community.

  • RTS,S: Safety and malaria transmission intensity studies, Post-Approval

  • The project aims to build capacity for an understanding of an interplay between genetic, epigenetic and environmental risk factors for obesity and associated cardiometabolic disease (CMD).

  • Analysis of Coverage of Fully Immunized Child (FIC), Associated Factors, Outcomes, and Impact Using Routinely Collected Population Cohort Data From 2001-2014

  • Developing a platform for reducing inequalities in health

  • At 1.2 billion, adolescents (10-19 year-olds) now make up one sixth of the world’s population. Nearly 90% of them live in low and middle-income (LMICs).

  • Addressing Inequities and Social Determinants of Health in Asia & Africa

  • Understand impact of universal health coverage on the poor and vulnerable

  • The MCTA was an INDEPTH Network project which aimed to strengthen clinical trial capacity, share results of real, on-the-ground trial activities and to codify best practices.

  • The overall objective is to develop the capacity of existing HDSSs in Africa to monitor the real life effects, including mortality, morbidity and growth, of our routine child health intervention programs.

  • The Wellcome Trust, UK has published a press release on its website on the Studies of the Epidemiology of Epilepsy in Demographic Sites (SEEDS)