Pneumococcal carriage in children under five years in Uganda

12 May 2017
Pneumonia is the major cause of death in children globally, with more than 900,000 deaths annually in children under five years of age. Streptococcus pneumoniae causes most deaths, most often in the form of community acquired pneumonia. Pneumococcal conjugate vaccines (PCVs) are currently being implemented in many low-income countries. PCVs decrease vaccine-type pneumococcal carriage, a prerequisite for invasive pneumococcal disease, and thereby affects pneumococcal disease and transmission. In Uganda, PCV was launched in 2014, but baseline data is lacking for pneumococcal serotypes in carriage.
This research published in the paper titled "Pneumococcal carriage in children under five years in Uganda-Will present pneumococcal conjugate vaccines be appropriate?" aimed to study pneumococcal nasopharyngeal carriage and serotype distribution in children under 5 years of age prior to PCV introduction in Uganda. It was found out that about half of circulating pneumococcal serotypes in carriage in the Ugandan under-five population studied was covered by available PCVs. Read more